At Dermoperfection, an award-winning clinic in the Mailbox, we believe that the most effective aesthetic treatments work with your body — not against it. That’s why we specialise in regenerative skincare: a new era of aesthetics that focuses on stimulating your body’s natural repair and rejuvenation processes.

From cutting-edge innovations like Purasomes Exosomes and Plinest Polynucleotides to results-driven technologies like EMFACE and Fractional CO2 Laser, we offer a carefully selected portfolio of treatments that are both clinically backed and naturally powerful.

What Is Regenerative Skincare?

Regenerative skincare is based on the principle of activating the body’s own ability to heal, restore, and regenerate — without invasive procedures or aggressive treatments. Whether the goal is collagen production, cellular repair, or tissue renewal, these treatments encourage a biological response that enhances skin health from within.

The result? Natural-looking, long-term improvements in skin tone, texture, elasticity, and radiance.

Our Most In-Demand Regenerative Treatments:

Purasomes Exosomes
A revolutionary cell signalling treatment that promotes skin regeneration and repair by delivering high concentrations of growth factors and peptides. Ideal for improving texture, elasticity, and signs of ageing.

Plinest Polynucleotides
Derived from purified DNA fragments, polynucleotides support tissue regeneration at a cellular level. This injectable treatment restores skin density, hydration, and elasticity — perfect for age-related skin concerns.

EMFACE
A non-invasive facial treatment that simultaneously lifts, tones, and tightens using synchronised radiofrequency and HIFES™ technology. Think of it as a needle-free facelift, with zero downtime.

Fractional CO2 Laser
This gold-standard resurfacing treatment works by stimulating collagen through controlled micro-injuries in the skin. It’s ideal for tackling fine lines, pigmentation, scarring, and skin laxity.

Natural Results, Backed by Science

Each of our regenerative treatments is medically approved, clinically proven, and carefully tailored to your skin’s individual needs. Whether you’re seeking preventative care, rejuvenation, or restorative treatment, Dermoperfection offers a safe and advanced approach to achieving your goals.

Our award-winning clinic is trusted by patients across Birmingham and beyond for delivering natural-looking results — without compromise. Book your consultation today and discover how regenerative skincare can unlock your skin’s full potential.

Skin Cancer Awareness Month is a crucial reminder of the risks associated with prolonged sun exposure—and the importance of protecting your skin year-round. While the focus is rightly on prevention and early detection, it’s also important to address the long-term impact of UV radiation, including sun damage that may already be visible on the skin.

At award-winning Dermoperfection, based on Level 2 of The Mailbox in Birmingham, we regularly treat patients concerned about the lasting effects of sun exposure. From pigmentation and dehydration to fine lines and skin laxity, sun damage often becomes more pronounced over time—especially after years of tanning or skipping SPF.

The good news? Modern aesthetic medicine offers clinically proven, non-surgical solutions to treat and reverse these visible signs while promoting long-term skin health.

What Does Sun Damage Look Like?

Even though a tan may seem like a short-term glow, the long-term effects of UV exposure can lead to significant damage at a cellular level. Common signs include:

• Hyperpigmentation or uneven skin tone

• Dry, crepey or thinning skin

• Premature lines and wrinkles

• Reduced elasticity and sagging

• Dullness or loss of radiance

It’s also important to note that UV exposure is the primary cause of photoaging, responsible for up to 80% of visible ageing. Over time, these changes can increase the risk of skin cancers—another reason why prevention and repair go hand-in-hand.

Treatments We Recommend to Reverse Sun Damage

1. Profhilo: Deep Hydration for Damaged Skin

Profhilo is an injectable treatment rich in hyaluronic acid, designed to hydrate from within and rejuvenate tired, UV-damaged skin.

• Ideal for crepey, sun-damaged skin

• Boosts collagen and elastin

• Improves tone, firmness and glow

It’s especially beneficial for skin that feels tight, dull, or prematurely aged due to chronic sun exposure.

2. Plinest Polynucleotides: Cellular Regeneration

Plinest is part of a new class of regenerative injectables that harness filtered DNA fragments to support skin healing at a cellular level.

• Reduces pigmentation and textural changes

• Repairs oxidative damage caused by UV rays

• Stimulates natural tissue repair

This is a powerful, medical-grade option for those seeking visible skin renewal after years of sun damage.

3. HydraFacial: Antioxidant-Rich Skin Detox

HydraFacial combines deep cleansing, exfoliation and antioxidant infusion in one non-invasive treatment.

• Brightens sun-damaged, dull skin

• Fades surface pigmentation

• Restores hydration and defences

It’s also an excellent maintenance treatment after holidays or summer months, helping you reset your skin health.

SPF: The Essential Daily Defence

While treatments can repair damage, prevention remains the most powerful tool in your skincare arsenal. A broad-spectrum, medical-grade SPF is vital for protecting against UVA (ageing) and UVB (burning) rays—and essential to maintain your treatment results.

Our top SPF picks include:

• Obagi Sun Shield Matte,  Tinted or Cool SPF50

• Mesoestetic Melan 130+ Pigment Control

• PCA Skin Weightless Protection SPF45

We stock these and more in-clinic and online, so your skin is protected every day.

Start Your Skin Recovery Journey

Whether you’re looking to correct signs of sun damage or take proactive steps in your skincare, Dermoperfection’s expert medical team is here to help. Visit our award-winning clinic at The Mailbox to create your bespoke skin plan or shop our recommended sun protection products online.

Protect. Repair. Rejuvenate.
This Skin Cancer Awareness Month, take action for healthier, more resilient skin—for today and the future.

Plinest HPT Polynucleotides for Hair! And enhanced recovery

Regenerate hair follicles with this biostimulation treatment to promote and restore scalp healthiness and as we’ve also found pre-hair transplant has contributed to the fast healing, recovery and hair growth due to having conditioned and well prepped foundations in the scalp for the new transplanted hair.

Plinest Polynucleotides are one of the most innovative and exciting treatments on the market. Thanks to their biostimulatory properties, they are able to regenerate your hair follicles to stimulate hair growth, regenerate the tissues in the scalp and anti inflammatory actions after just a few treatments.

WATCH THE REEL HERE! 

The eye area needs a regenerative boost — and Plinest Polynucleotides deliver just that. Formulated with purified salmon trout DNA, this advanced treatment supports skin repair, improves pigmentation, and enhances overall skin quality.

Book a consultation with our medical experts in the Mailbox today!

WATCH THE REEL HERE!

Patsy Palmer has been showing off her impressive results with EMFACE – and we’re Birminghams leading EMFACE clinic!

EMFACE is a cutting-edge, non-invasive treatment that lifts and sculpts the face by stimulating collagen, elastin, and facial muscles – all without needles or downtime.

We also have ready the latest addition to EMFACE – The brand new EMFACE Eyes treatment, targeting the under-eye area to reduce puffiness, fine lines, dark circles and more for a refreshed appearance

Book your consultation with our medical experts to find out more today!

WATCH THE REEL HERE!

At Dermoperfection, we offer 88 expert treatments, delivering state-of-the-art, industry-leading, science-backed care with award-winning results, 7 days a week!

🏆PCA Skin’s Clinic of the Year 2024
🏆GHP Global Excellence Award: Best Aesthetic Clinic in Birmingham
🏆WhatClinic Patient Service Award 2024

Our expert team provides tailored treatment plans to achieve your skin and body goals.

Ready for the best? Book your consultation at our award-winning clinic in the Mailbox today!

WATCH THE REEL HERE FOR MORE!

Our SmartXEL Fractional CO2 Laser is transforming skin with proven results.
✨Improved texture
✨Reduced pore size
✨Faded scars
✨Boosted luminosity and collagen

This evidence-based, gold standard treatment is delivering exceptional outcomes for our patients. Book a consultation today with our medical experts!

WATCH THE REEL AND SEE THE RESULTS FOR YOURSELF HERE!

A little Lip tweak….. the art of adding to a fuller lip, retaining a natural-looking result and feel.

We’re already working with a naturally fuller juicy lip, so the brief was simply just adding a bit of plump and shape.

Framing the outer edge and plumping up the cupid’s bow was just the perfect outcome to this lip tweak.

Using AliaxinFL we achieved this result, knowing that this is a superb product that will support natural integration into the delicate lip tissues.

Aliaxin FL is a hyaluronic acid-based dermal filler which is the specific treatment for lips and the lip contour, as it has an ideal thickness and consistency for restoring firmness and natural definition. It also has hydrating properties to keep the treated lip healthy and protected.

WATCH THE REEL HERE

Say goodbye to puffiness, fine lines, and dark circles, with zero needles and zero downtime. EMFACE Eyes delivers lifted, firmer, and brighter under-eyes in just 20 minutes. It’s the ultimate non-invasive treatment to refresh and rejuvenate your eye area.

Book your consultation with our medical experts at Dermoperfection today!

WATCH THE REEL HERE

We all want radiant, youthful-looking skin—but with busy schedules, most of us are looking for treatments that deliver immediate results, while also supporting longer-term skin health. At Dermoperfection, we offer advanced treatments designed to soften fine lines and wrinkles quickly, with continued results that improve over time.

Here are five of our favourite anti-ageing treatments that show visible results straight away—and keep getting better with time.

1. Anti-Wrinkle Injections (Botox)

If you’re looking for a go-to treatment to smooth dynamic wrinkles, Botox (anti-wrinkle injections) is the classic choice, and for good reason. It works by temporarily relaxing the facial muscles responsible for fine lines and creases, particularly on the forehead, around the eyes (crow’s feet), and frown lines.

• Results in: 3–7 days 
• Longevity: Up to 3–4 months 
• Why we love it: Instant softening effect and a refreshed, lifted appearance without surgery.

2. EMFACE Eyes

For those targeting the delicate eye area, EMFACE Eyes is a revolutionary non-invasive treatment that combines radiofrequency and HIFES technology to lift, tone and smooth, without needles.

It stimulates collagen production and muscle tone around the eyes, giving a natural, wide-awake, lifted look.

• Results in: Immediately visible tightening after first session 
• Longevity: Results build and peak over 6–12 weeks 
• Why we love it: Needle-free eye rejuvenation with visible firming and smoothing effects from the first session.

3. Polynucleotides (Plinest)

Known famously as the “fish sperm facial”, Polynucleotides are a powerful skin regenerative treatment derived from salmon trout DNA. These injectables are ideal for delicate areas like under the eyes, neck and décolletage, where skin often loses its elasticity first.

• Results in: Skin hydration immediately after treatment 
• Longevity: Cellular regeneration continues for weeks post-treatment 
• Why we love it: It boosts skin quality at a deep level and delivers long-term rejuvenation, not just a quick fix.

4. Profhilo

A game-changer in injectable skincare, Profhilo is not your typical filler, it’s a skin booster that fills your skin with high concentrations of hyaluronic acid, stimulating collagen and elastin production for firmer, more hydrated skin.

• Results in: Glowing, plumper skin in just a few days 
• Longevity: Peak results after 2 sessions, lasting up to 6 months 
• Why we love it: Immediate glow, long-term firmness, especially great for crepey skin and dullness.

5. HydraFacial

The HydraFacial is a favourite for a reason, it’s the ultimate skin refresh with no downtime. This multi-step facial deeply cleanses, exfoliates, and hydrates while infusing the skin with antioxidants and peptides.

• Results in: Instantly brighter, smoother, more hydrated skin 
• Longevity: Ongoing improvements with regular sessions 
• Why we love it: Instant red-carpet glow and the perfect prep before any big event or special occasion.

At Dermoperfection, we’re all about evidence-based treatments with real results. Whether you’re after a quick boost before a big event or want to invest in long-term skin health, our medical experts are here to help you find the perfect plan. Book consultation today and get started on your journey to visibly smoother, younger-looking skin