At Dermoperfection, we offer 88 expert treatments, delivering state-of-the-art, industry-leading, science-backed care with award-winning results, 7 days a week!

🏆PCA Skin’s Clinic of the Year 2024
🏆GHP Global Excellence Award: Best Aesthetic Clinic in Birmingham
🏆WhatClinic Patient Service Award 2024

Our expert team provides tailored treatment plans to achieve your skin and body goals.

Ready for the best? Book your consultation at our award-winning clinic in the Mailbox today!

WATCH THE REEL HERE FOR MORE!

We all want radiant, youthful-looking skin—but with busy schedules, most of us are looking for treatments that deliver immediate results, while also supporting longer-term skin health. At Dermoperfection, we offer advanced treatments designed to soften fine lines and wrinkles quickly, with continued results that improve over time.

Here are five of our favourite anti-ageing treatments that show visible results straight away—and keep getting better with time.

1. Anti-Wrinkle Injections (Botox)

If you’re looking for a go-to treatment to smooth dynamic wrinkles, Botox (anti-wrinkle injections) is the classic choice, and for good reason. It works by temporarily relaxing the facial muscles responsible for fine lines and creases, particularly on the forehead, around the eyes (crow’s feet), and frown lines.

• Results in: 3–7 days 
• Longevity: Up to 3–4 months 
• Why we love it: Instant softening effect and a refreshed, lifted appearance without surgery.

2. EMFACE Eyes

For those targeting the delicate eye area, EMFACE Eyes is a revolutionary non-invasive treatment that combines radiofrequency and HIFES technology to lift, tone and smooth, without needles.

It stimulates collagen production and muscle tone around the eyes, giving a natural, wide-awake, lifted look.

• Results in: Immediately visible tightening after first session 
• Longevity: Results build and peak over 6–12 weeks 
• Why we love it: Needle-free eye rejuvenation with visible firming and smoothing effects from the first session.

3. Polynucleotides (Plinest)

Known famously as the “fish sperm facial”, Polynucleotides are a powerful skin regenerative treatment derived from salmon trout DNA. These injectables are ideal for delicate areas like under the eyes, neck and décolletage, where skin often loses its elasticity first.

• Results in: Skin hydration immediately after treatment 
• Longevity: Cellular regeneration continues for weeks post-treatment 
• Why we love it: It boosts skin quality at a deep level and delivers long-term rejuvenation, not just a quick fix.

4. Profhilo

A game-changer in injectable skincare, Profhilo is not your typical filler, it’s a skin booster that fills your skin with high concentrations of hyaluronic acid, stimulating collagen and elastin production for firmer, more hydrated skin.

• Results in: Glowing, plumper skin in just a few days 
• Longevity: Peak results after 2 sessions, lasting up to 6 months 
• Why we love it: Immediate glow, long-term firmness, especially great for crepey skin and dullness.

5. HydraFacial

The HydraFacial is a favourite for a reason, it’s the ultimate skin refresh with no downtime. This multi-step facial deeply cleanses, exfoliates, and hydrates while infusing the skin with antioxidants and peptides.

• Results in: Instantly brighter, smoother, more hydrated skin 
• Longevity: Ongoing improvements with regular sessions 
• Why we love it: Instant red-carpet glow and the perfect prep before any big event or special occasion.

At Dermoperfection, we’re all about evidence-based treatments with real results. Whether you’re after a quick boost before a big event or want to invest in long-term skin health, our medical experts are here to help you find the perfect plan. Book consultation today and get started on your journey to visibly smoother, younger-looking skin

In-depth education, live demonstrations, 150+ giveaways, exclusive product launches, expert skin advice and more at our event last week in collaboration with DermaFocus and Plinest.

Thank you to everyone who joined us and got involved – we loved welcoming you!

We look forward to seeing you at our next event!

WATCH HERE!

We recently hosted an exclusive VIP evening with DermaFocus to celebrate the latest in regenerative aesthetics.

We spoke to some of our amazing guests on the night – here’s what they had to say!

WATCH HERE!

From pigmentation to acne scarring, the answers were honest and relatable — do you find you have similar concerns, or something else entirely?

Book a consultation with our medical experts at The Mailbox. We’ll analyse your skin and create a personalised treatment plan tailored to your needs.

WATCH HERE!

In the ever-evolving world of aesthetics, the future of skincare is already here—and it’s happening at the cellular level. If you’ve been hearing the buzz around Plinest Polynucleotides and Purasomes Exosomes, you’re not alone. These two treatments are leading a new wave in regenerative skin health, offering natural rejuvenation by working with your body, not against it.

But what exactly are cellular-level treatments — and why are they all the rage?

What Are Cellular-Level Treatments?

Cellular-level treatments target the skin’s innermost structures to stimulate repair, regeneration, and renewal from the inside out. Unlike surface-level procedures that focus on exfoliation or temporary plumping, these advanced treatments work deep within the skin to improve the function and vitality of skin cells themselves.

The stars of Regeneration are Plinest Polynucleotides and Purasomes Exosomes

Plinest is a regenerative injectable made from purified polynucleotides (derived from salmon trout DNA), known for their powerful ability to stimulate fibroblasts—cells responsible for producing collagen, elastin, and hyaluronic acid.

Benefits of Plinest polynucleotides:

• Improves skin elasticity and firmness
• Boosts hydration from within
• Reduces fine lines and signs of ageing
• Repairs damage and inflammation (ideal for acne scarring or rosacea-prone skin) 

Plinest is often referred to as a “bio-revitaliser” because it doesn’t just mask issues—it revitalises the skin at a cellular level, encouraging it to function like younger, healthier skin.

Exosomes are tiny extracellular vesicles naturally released by cells. Purasomes harness this power using stem-cell-derived exosomes, packed with growth factors, peptides, and cytokines that supercharge your skin’s natural repair mechanisms.

Why Purasomes are trending:

• Enhances skin cell communication for faster healing
• Brightens and evens skin tone
• Reduces inflammation and sensitivity
• Great for post-treatment recovery or general skin rejuvenation

Why These Two Are the Ultimate Pairing

Plinest polynucleotides and Purasomes exosomes are the dream team of regenerative skincare. Used together, they provide a multi-layered approach to rejuvenation:

• Plinest restores the structure and integrity of the skin
• Purasomes accelerate healing, brighten, and reduce inflammation 

It’s no wonder these two treatments are favoured by celebrities, patients and medical experts. They represent the next generation of skin treatments—natural, science-backed, and results-driven. Book a consultation today at our award-winning clinic!

If you are considering this treatment, learn more about polynucleotides in Birmingham at our city centre clinic.

We asked the public at The Mailbox — and then we turned to medical expert, Rebecca from DermaFocus, to explain what regenerative really means in the world of aesthetics.

Not sure yourself? Book a consultation to discover a cutting-edge approach to skin health

WATCH HERE

April is Rosacea Awareness Month, and we are teaming up with DermaFocus with a showcase event to raise awareness of this common, yet often misunderstood skin condition. 

Rosacea affects millions of people worldwide, causing persistent redness, sensitivity, and flare-ups that can impact confidence and overall skin health. At Dermoperfection, we are committed to providing the most advanced skincare solutions to help manage concerns like Rosacea. That’s why we are hosting a special week-long event in collaboration with DermaFocus, the creators of the award-winning Plinest polynucleotides and innovative exosome treatments.

What to Expect 

From the 9th to the 11th of April, we are inviting you to join us on Level 2, The Mailbox, located infront of Harvey Nichols and opposite Medicine Bakery, for a unique skincare experience. 

Featuring live demonstrations of cutting-edge treatments, giving you exclusive access to see first-hand how Plinest Polynucleotides and Exosomes can aid regeneration. Our expert practitioners will be on hand to offer in-depth skincare advice, guiding you through the best treatment options for Rosacea-prone and sensitive skin.

We will be welcoming guest speakers, to share their insights into the latest advancements in skincare and aesthetic medicine.  Expect exclusive giveaways, live demos, expert skincare advice, and much more. 

Why Plinest Polynucleotides & Exosomes?

We are pleased to showcase two revolutionary skincare advancements: Plinest polynucleotides and Exosomes, both leading in-clinic treatments for their regeneration and restorative properties.

Plinest, recently awarded Injectable Product of the Year at the 2025 Aesthetic Awards, is formulated with polynucleotides, naturally occurring molecules that deeply hydrate, repair, and strengthen the skin. 

These powerful ingredients help reduce inflammation, making Plinest an excellent treatment for those with sensitive and rosacea-prone skin. Additionally, polynucleotides work to stimulate collagen production, improving skin texture, elasticity, and overall health.

Exosomes, the latest breakthrough in regenerative skincare. These microscopic extracellular vesicles enhance cell-to-cell communication, delivering powerful growth factors, antioxidants, and anti-inflammatory benefits to the skin. Exosomes work alongside polynucleotides to accelerate healing, boost collagen synthesis, and restore skin balance, making them an ideal solution for individuals struggling with redness, irritation, and compromised skin barriers.

By combining Plinest Polynucleotides with Exosomes, we offer a next-generation approach to treating Rosacea and enhancing overall skin health.

The Importance of Rosacea Awareness Month

Rosacea Awareness Month is all about educating and empowering individuals who experience this chronic skin condition. Many people struggle to find effective solutions, but with advancements like Plinest polynucleotides and exosome therapy, there are now clinically proven treatments that can make a real difference.

This event is a fantastic opportunity to learn more about how to manage rosacea and discover the latest innovations in skin health and rejuvenation. We encourage everyone to take part, whether you personally experience rosacea or know someone who does. By attending, you will gain valuable skincare knowledge, expert advice, and access to exclusive treatment offers.

Join Us and Discover the Future of Aesthetics

This is an event you won’t want to miss! Join us between 9th–11th April at Dermoperfection, The Mailbox, and discover the benefits of Plinest Polynucleotides and Exosomes.

This Mother’s Day, why not gift yourself or the special mother figure in your life the gift of self-care with advanced, results-driven treatments designed to enhance natural beauty and boost confidence at every stage of motherhood. 

Whether you’re looking to restore firmness, tackle tired eyes, or feel more confident in your body, our range of clinically proven procedures will help you look and feel your best.

Tailored Treatments for Every Mother:

At Dermoperfection, we understand that each patient has unique needs, which is why we offer a variety of treatments to support skin and body health. From rejuvenating tired skin to sculpting and toning the body, we’ve got you covered with options that deliver noticeable results.

1. Non-Invasive Body Sculpting with EMSCULPT Neo:

Achieve a toned, sculpted physique with EMSCULPT Neo, a non-invasive treatment that simultaneously burns fat and builds muscle. Whether you’re looking to enhance your abdominal area, tone your arms, or firm up your legs, this innovative procedure is designed to shape your body without any downtime.

2. Cellulite Smoothing with EMTONE:

Say goodbye to stubborn cellulite with EMTONE! This powerful treatment targets and reduces the appearance of cellulite, leaving your skin smoother and more youthful-looking. Perfect for mums who want to feel confident in their skin again, EMTONE is a non-invasive solution that works to restore skin’s texture and elasticity.

3. Under-Eye Rejuvenation with EMFACE Eyes:

Mothers often experience the tell-tale signs of sleepless nights with under-eye bags and puffiness. EMFACE Eyes is the perfect treatment to refresh and rejuvenate the delicate skin around the eyes, reducing puffiness and dark circles for a more rested and radiant look. It’s an ideal solution for mums who need a quick pick-me-up!

4. Polynucleotides for Skin Repair:

Restore your skin’s vitality and hydration with polynucleotides. This award-winning treatment stimulates collagen production, promoting skin repair and regeneration. It’s particularly effective for tackling signs of ageing, improving skin elasticity, and restoring a youthful glow to tired, stressed skin

5. Collagen Stimulation with SQT Bio Microneedling:

Reinvigorate your skin with SQT Bio Microneedling, a treatment that promotes collagen production and skin regeneration. By using fine needles to create tiny micro-channels in the skin, this treatment enhances skin texture, reduces fine lines, and helps tackle pigmentation for a smoother, more even complexion.

This Mother’s Day, unlock the ultimate gift: to feel rejuvenated, confident, and refreshed. Whether you’re looking to enhance your skin’s health, sculpt your body, or rejuvenate tired eyes, we have the perfect treatment tailored to your needs.

Not quite sure what the right treatment is to have or gift? Get in contact with our medical experts who will help guide you every step of the way.

This past weekend, the aesthetics industry celebrated its finest at The Aesthetic Awards 2025, one of the most prestigious events in the aesthetic medicine calendar. The awards recognise the very best in clinical excellence, innovation, and patient care across the UK.

At Dermoperfection, we are proud to offer treatments and skincare that not only deliver outstanding results for our patients but are also recognised by leading industry experts. This year, two of the most trusted and transformative names in our clinic took home top accolades!

Injectable Product of the Year: Plinest Polynucleotides by Dermafocus

Leading the way in skin regeneration, Plinest by Mastelli and distributed by Dermafocus was awarded Injectable Product of the Year at this year’s ceremony.

The judges praised Plinest for its exceptional clinical results and detailed evidence showcasing excellent customer support and satisfaction. One judge even commented that this entry alone convinced them to incorporate the product into their own practice!

But what makes Plinest polynucleotides stand out?

Plinest harnesses advanced biotechnology with purified polynucleotides, naturally occurring molecules that stimulate tissue repair, enhance hydration, and promote skin regeneration. It’s a revolutionary treatment designed to restore skin quality, improve elasticity, and deliver a youthful glow, all while supporting the skin’s natural healing process.

At Dermoperfection, we use Plinest to treat fine lines, wrinkles, dullness, and skin laxity. It’s an ideal solution for patients seeking skin revitalisation with clinically proven results.

Skin Product/Range of the Year: Obagi Medical

Another of our clinic favourites, Obagi Medical, took home Skin Product/Range of the Year, reaffirming its place as a global leader in medical-grade skincare.

The judges and voters highlighted Obagi Medical’s dedication to dermatological advancements, noting its scientifically backed formulations and transformative results. Obagi’s commitment to using high-quality, medical-grade ingredients ensures its effectiveness in treating a wide range of skin concerns, from hyperpigmentation and acne to ageing and sun damage.

At Dermoperfection, we trust Obagi to deliver comprehensive skincare solutions tailored to our patients’ individual needs. Whether you’re looking for powerful skin brightening, age-defying formulations, or a routine that helps maintain long-term skin health, Obagi Medical provides the tools to achieve radiant, healthy skin.

Experience Award-Winning Skincare and Treatments at Dermoperfection

We are proud to offer both Plinest Polynucleotides and Obagi Medical at our award-winning clinic in Birmingham. These industry-recognised products and treatments are part of our commitment to delivering medical-grade skincare and advanced injectable treatments, all tailored to you by our team of medically trained aesthetic experts. Book a consultation today and discover how these award-winning innovations can transform your skin.